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Long-term use of accutane is believed to cause certain side effects.

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Notify your healthcare provider immediately if you develop any serious Accutane side effects,.Isotretinoin I took Accutane back in 2010 for really bad acne.These side effects may go away during treatment as your body adjusts to the medicine.Please upgrade your browser for the best Refinery29 experience. Read more. Accutane (and its side effects) are serious business.

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